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Acid Halides to Alcohols: Grignard Reaction01:15

Acid Halides to Alcohols: Grignard Reaction

Organomagnesium halides, commonly known as Grignard reagents, convert acid halides to tertiary alcohols. The reaction requires two equivalents of the Grignard reagent and proceeds via a ketone intermediate.
Grignard reagents are a source of carbanions and function as nucleophiles. The mechanism begins with the nucleophilic attack by the carbanion at the carbonyl carbon of the acid halide to form a tetrahedral intermediate. Next, the carbonyl group is re-formed, and the halide ion departs,...

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Related Experiment Video

Updated: Jun 7, 2026

Generation of Alginate Microspheres for Biomedical Applications
10:33

Generation of Alginate Microspheres for Biomedical Applications

Published on: August 12, 2012

Alginates as impression material

E CEPERO BONILLA

    Protesis Clinica; Periodico Tecnico Informativo Para La Profesion Dental
    |October 29, 2010
    PubMed
    Summary

    No abstract available in PubMed .

    Keywords:
    TEETH/prostheses

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