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Future sexual medicine physiological treatment targets
Arthur L Burnett1, Irwin Goldstein, Karl-Erik Andersson
1The James Buchanan Brady Urological Institute, The Johns Hopkins Hospital, Baltimore, MD, USA. aburnett@jhmi.edu
The Journal of Sexual Medicine
|October 30, 2010
Summary
Understanding sexual function requires knowledge of molecular and cellular targets. Future treatments for sexual dysfunction may involve gene therapy, stem cell therapy, and regenerative medicine.
Area of Science:
- Sexual medicine
- Physiology
- Molecular biology
Background:
- Sexual function involves complex interactions of the nervous, vascular, and endocrine systems.
- Evolving research highlights the need for updated information on molecular and biological mechanisms governing sexual physiology.
Purpose of the Study:
- To create an evidence-based consensus report on current knowledge of cellular and molecular targets in sexual physiology.
- To consolidate expert opinions on the biological systems underlying sexual function.
Main Methods:
- A 2-year consensus process involving seven experts from four countries.
- Expert opinions were formed by grading medical literature and through committee discussions, presentations, and debates.
Main Results:
- Current knowledge of major cellular and molecular targets governing sexual physiology is presented.
- Future therapeutic strategies may include growth factor therapy, gene therapy, stem/cell-based therapies, and regenerative medicine.
Conclusions:
- Scientific advancements are crucial for developing novel and effective treatments for sexual dysfunction.
- Exploring broad physiological directions is essential for the future management of sexual disorders.
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