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In Vivo Imaging Systems (IVIS) Detection of a Neuro-Invasive Encephalitic Virus
Published on: December 2, 2012
Enterovirus 75 encephalitis in children, southern India.
Penny Lewthwaite1, David Perera, Mong How Ooi
1Division of Neurological Science, University of Liverpool, Liverpool, UK. pennylewthwaite@doctors.org.uk
Emerging Infectious Diseases
|October 30, 2010
Summary
Enterovirus 75 caused acute encephalitis in 5 Indian children. Throat swabs showed promise for diagnosing this enterovirus infection, addressing diagnostic challenges in Southeast Asia.
Area of Science:
- Virology
- Pediatric Infectious Diseases
- Neurology
Background:
- Enterovirus outbreaks in Southeast Asia highlight diagnostic challenges.
- Acute encephalitis syndrome (AES) in children requires accurate etiological diagnosis.
Purpose of the Study:
- To identify the causative agent in children with acute encephalitis syndrome in southern India.
- To investigate the potential role of enterovirus 75 in pediatric encephalitis.
Main Methods:
- Retrospective analysis of 106 children diagnosed with acute encephalitis syndrome between 2005 and 2007.
- Diagnostic testing of throat swab specimens.
Main Results:
- Enterovirus 75 was identified in 5 (4.7%) of the children with AES.
- The findings suggest enterovirus 75 as a potential cause of pediatric encephalitis.
Conclusions:
- Enterovirus 75 is an identified cause of acute encephalitis syndrome in Indian children.
- Throat swab specimens are a viable method for diagnosing enterovirus 75 infections.
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