Related Experiment Video
Updated: Jun 7, 2026
Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
Published on: May 17, 2019
[Expression and significance of P311 and ITGB4BP in non-small cell lung cancer]
Chun-lan Tang1, Shun-zong Yuan, He-ping Yang
1Department of respiratory Diseases, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
Objective:
The aim of this study was to investigate the expression and significance of P311 and ITGB4BP in non-small cell lung cancer (NSCLC).
Methods:
Tissue microarrays were prepared from 80 NSCLC specimens and examined by immunohistochemistry.
Results:
The positive rates of P311 and ITGB4BP expression were 77.5% (62/80) and 82.5% (66/80), respectively. The double positive expression rate was 73.8% (59/80). The consistency rate was 87.5%, and there was a significant consistency between P311 and ITGB4BP expressions (Kappa = 0.611, P < 0.001).
Conclusion:
There may be a new signaling pathway P311-ITGB4BP in NSCLC, and it may regulate the lung cancer cell migration.