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Updated: Jun 7, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
[Analysis on the background of arising of Evidence-based medicine]
Yu Xie1, Chang-lin Ai, Shao-lin Deng
1China Center for Evidence-Based Medicine, Sichuan University, Chengdu 610041, China.
Abstract:
Science is coming from the background of social culture. Evidence-based medicine (EBM) was generated at the early 90's of 20th Century, and there were some landmark things before its appearance. The background of EBM included: (1) risk control of medical techniques at the 70s of 20th Century; (2) ethical ideas of Protestant, including secularism, rationalism and utilitarianism; (3) British positivism and its tradition.
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