Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

How do neuropeptides alter cognitive performance?

A Sahgal1

  • 1MRC Neurochemical Pathology Unit, Newcastle General Hospital, Newcastle-upon-Tyne, U.K.

Polish Journal of Pharmacology and Pharmacy
|November 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Minimal clinically important differences in the Spine Oncology Study Group Outcomes Questionnaire (SOSGOQ2.0) in patients with symptomatic spinal metastases.

The spine journal : official journal of the North American Spine Society·2026
Same author

Boosting the Evidence: Time to Integrate Simultaneous Integrated Boost in Spine Stereotactic Body Radiotherapy?

Clinical oncology (Royal College of Radiologists (Great Britain))·2025
Same author

Response to "Are roots really not worth considering?"

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2024
Same author

ESTRO clinical practice guideline: Stereotactic body radiotherapy for spine metastases.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2023
Same author

Efficacy and safety of SBRT for spine metastases: A systematic review and meta-analysis for preparation of an ESTRO practice guideline.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2023
Same author

Stereotactic Body Radiotherapy for Painful Spinal Metastases - A Significant Advance in the Field of Radiation Oncology.

Clinical oncology (Royal College of Radiologists (Great Britain))·2022
Same journal

Melatonin in vertebrate retina: biosynthesis, receptors and functions.

Polish journal of pharmacology and pharmacy·1992
Same journal

Circadian changes in the elimination of amitriptyline in rats.

Polish journal of pharmacology and pharmacy·1992
Same journal

Circadian variations of phenacetin metabolism in rats in vivo and in vitro.

Polish journal of pharmacology and pharmacy·1992
Same journal

Circadian changes of cytochrome P-450-dependent monooxygenase system in the rat liver.

Polish journal of pharmacology and pharmacy·1992
Same journal

The role of GABA-ergic signal in the regulation of melatonin biosynthesis in vertebrate retina.

Polish journal of pharmacology and pharmacy·1992
Same journal

Structure-activity relationship studies of CNS agents. Part VIII. Bulk tolerance around the protonation center of 4-substituted 1-(3-chlorophenyl)piperazines at 5-HT1A and 5-HT2 receptors.

Polish journal of pharmacology and pharmacy·1992
See all related articles

Cognitive enhancers must improve intrinsic neural capacity, not just motivation. This study distinguishes between true cognitive enhancement and arousal effects, highlighting the need for specific research methods.

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Pharmacology

Background:

  • Cognitive performance relies on intrinsic neural capacity and motivational factors like arousal.
  • Distinguishing between these factors is crucial for identifying true cognition enhancers.
  • Current research often conflates arousal effects with genuine cognitive improvements.

Purpose of the Study:

  • To differentiate between substances that enhance intrinsic cognitive capacity and those that affect motivational processes.
  • To critically evaluate the criteria for classifying a substance as a true cognition enhancer.
  • To discuss the role of neuropeptides, such as vasopressin, in modulating arousal and motivation.

Main Methods:

  • Conceptual analysis of cognitive performance parameters.

Related Experiment Videos

  • Review of evidence on neuropeptide effects on arousal and motivation.
  • Discussion of a theoretical model for separating cognitive and motivational effects.
  • Emphasis on the need for specific experimental designs.

    • Main Results:

    • Cognitive enhancers should exclusively target intrinsic neural capacity.
    • Neuropeptides like vasopressin may primarily influence motivational and arousal processes.
    • A plausible mechanism for neuropeptide action on arousal is proposed.

    Conclusions:

    • True cognition enhancement requires improvement in the nervous system's intrinsic capacity.
    • Substances affecting arousal or motivation alone are not considered true enhancers.
    • Further research with refined methodologies is necessary to isolate and measure cognitive enhancement effects.