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Updated: Aug 12, 2026

Examination of Rapid Dopamine Dynamics with Fast Scan Cyclic Voltammetry During Intra-oral Tastant Administration in Awake Rats
Published on: August 12, 2015
[Evaluation of pyralgin usefulness in premedication of patients before stomatological treatment]
Abstract:
Pyralgin (metamizole sodium) usefulness was tested in premedication of 90 patients subjected to processing of hard tooth tissues by grinding or drilling. The results of the study demonstrated that about 2/3 of the patients failed to observe any difference in the painfulness of the procedure with and without premedication with Pyralgin. In 1/3 of the patients Pyralgin reduced pain, improved wellbeing and raised the emotional status during the procedure. This effect might be regarded as a placebo result.
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