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Published on: June 21, 2019
The role of prophylactic anticonvulsants in moderate to severe head injury
Arshad Ali Khan1, Ashis Banerjee
1Chase Farm Hospital, The Ridgeway, Enfield, EN2 8JL UK.
Background:
Post-traumatic seizures cause secondary brain injury, contributing to morbidity and mortality after traumatic brain injury. Seizure activity may be undetectable if the patient is paralysed and ventilated.
Aims:
The effect of prophylactic anticonvulsant therapy on the prevention of seizures after moderate to severe traumatic brain injury was studied.
Methods:
A structured systematic literature review was performed.
Results:
There may be a place for prophylactic anticonvulsants in the prophylaxis of early post-traumatic seizures.
Conclusion:
Further randomised controlled trials are needed to firmly establish the benefits of prophylactic anticonvulsants.
