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Updated: Jun 7, 2026

A Data-Driven Approach to Quantifying Immune States in Sepsis
Published on: February 7, 2025
Data driven computing by the morphing fast Fourier transform ensemble Kalman filter in epidemic spread simulations
Jan Mandel1, Jonathan D Beezley, Loren Cobb
1Department of Mathematical and Statistical Sciences, University of Colorado Denver, Denver, CO 80217-3364, USA.
Abstract:
The FFT EnKF data assimilation method is proposed and applied to a stochastic cell simulation of an epidemic, based on the S-I-R spread model. The FFT EnKF combines spatial statistics and ensemble filtering methodologies into a localized and computationally inexpensive version of EnKF with a very small ensemble, and it is further combined with the morphing EnKF to assimilate changes in the position of the epidemic.
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