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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

[Sepsis at an internal medicine department]

J Gómez Gómez1, A Alemán Lorenzo, J L Hernández Cardona

  • 1C. S. Virgen de la Arrixaca, Departamento de Medicina Interna, Facultad de Medicina, Murcia.

Anales De Medicina Interna (Madrid, Spain : 1984)
|January 1, 1990
PubMed

Insights

This study analyzed 185 bacteremia cases, identifying common pathogens like Staphylococcus aureus and Streptococcus pneumoniae. Nosocomial infections were linked to Klebsiella pneumoniae and Pseudomonas aeruginosa, with factors like age and shock increasing mortality risk.

Area of Science:

  • Clinical Microbiology
  • Infectious Diseases
  • Epidemiology

Context:

  • Retrospective analysis of 185 bacteremia cases admitted to internal medicine.
  • Study conducted at "C.S. Virgen de la Arrixaca" in Murcia between 1977 and 1986.
  • Focus on differentiating common and nosocomial infection-causing pathogens.

Purpose:

  • To identify the etiological agents of bacteremia.
  • To determine the association of specific bacteria with common vs. nosocomial infections.
  • To identify risk factors for increased mortality in bacteremia patients.

Summary:

  • Common bacteremia was significantly associated with Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus A group, and Neisseria meningitidis.
  • Nosocomial bacteremia showed associations with Klebsiella pneumoniae, Serratia marcescens, Pseudomonas aeruginosa, Staphylococcus epidermidis, and Enterobacter.
  • No significant differences were found for E. coli and Proteus mirabilis between common and nosocomial infections.
  • Mortality risk factors included age over 40, nosocomial origin, Pseudomonas aeruginosa, severe comorbidities, acute clinical presentation, shock, and inadequate antibiotic therapy.

Impact:

  • Provides insights into the changing landscape of bacteremia pathogens over a decade.
  • Highlights distinct etiological profiles for community-acquired versus hospital-acquired bacteremia.
  • Identifies critical factors influencing bacteremia patient outcomes, informing clinical management and public health strategies.

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