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Related Experiment Videos

[Bacteremia of cutaneous origin].

J C Soriano Giménez1, S Tomás Vecina, J Torne Cachot

  • 1Servicio de Medicina Interna, Hospital del Mar. Universidad Autónoma de Barcelona.

Anales De Medicina Interna (Madrid, Spain : 1984)
|August 1, 1990
PubMed
Summary

Cutaneous bacteremia, often originating from skin conditions like decubitus ulcers, presents a significant mortality risk, especially in older patients with comorbidities. Early clinical suspicion and appropriate antibiotic therapy are crucial for improving outcomes in these bloodstream infections.

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Area of Science:

  • Infectious Diseases
  • Dermatology
  • Critical Care Medicine

Context:

  • Bacteremia, a bloodstream infection, poses a serious health threat.
  • Cutaneous sources of bacteremia are often underestimated.
  • Understanding the epidemiology and outcomes of skin-origin bacteremia is vital for clinical practice.

Purpose:

  • To analyze the incidence, characteristics, and outcomes of bacteremia originating from cutaneous sources.
  • To identify risk factors for mortality in patients with skin-related bloodstream infections.

Summary:

  • A 2-year study identified 558 bacteremia episodes, with 17 (3%) of cutaneous origin.
  • Commonly associated skin conditions included decubitus ulcers and cellulitis.
  • Key bacteria were Group A Streptococcus, Staphylococcus aureus, and Escherichia coli.

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  • Mortality was high at 47%, with sepsis-related deaths in 29% of cases.
  • Prognostic factors for death included advanced age, diabetes, gram-negative bacteria, and delayed/inadequate treatment.

    • Impact:

    • Highlights the significant morbidity and mortality associated with cutaneous bacteremia.
    • Emphasizes the need for heightened clinical suspicion for skin-related bloodstream infections.
    • Informs antibiotic stewardship and treatment strategies for these challenging infections.