Related Experiment Video

Updated: Jun 7, 2026

A Protocol for Analyzing Hepatitis C Virus Replication
13:04

A Protocol for Analyzing Hepatitis C Virus Replication

Published on: June 26, 2014

Hepatitis C virus co infection in HIV positive patients

T M Balogun1, S Emmanuel, K O Wright

  • 1Department of Haematology & Blood Transfusion, Lagos State University Teaching Hospital, 1-5 Oba Akinjobi Road, P.M.B.21105, Ikeja, Lagos, Nigeria. taiwo_modupe@yahoo.com

Nigerian Quarterly Journal of Hospital Medicine
|November 2, 2010
PubMed

Insights

Hepatitis C virus (HCV) co-infection is highly prevalent in HIV-positive individuals, posing increased health risks. This study found a 13-fold higher risk of HCV co-infection among HIV patients compared to blood donors.

Area of Science:

  • Infectious Diseases
  • Virology
  • Public Health

Background:

  • Hepatitis C virus (HCV) co-infection is common in individuals with HIV.
  • HCV co-infection significantly increases morbidity and mortality in HIV-positive populations.

Purpose of the Study:

  • To determine the prevalence of antibodies to HCV (anti-HCV) in HIV-positive patients.
  • To assess the rate of HIV/HCV co-infection.

Main Methods:

  • A cross-sectional study involving HIV-positive patients and HIV-negative blood donors.
  • HIV diagnosis using rapid kits and ELISA.
  • HCV antibody screening using ELISA kits for all subjects.

Main Results:

  • Anti-HCV antibodies were detected in 14.7% of HIV-positive patients and 1.1% of HIV-negative blood donors.
  • The HIV/HCV co-infection rate was highest in the 30-39 years age group.
  • A 13-fold higher risk of HCV co-infection was observed in HIV-positive patients.

Conclusions:

  • HIV-positive patients exhibit a high prevalence of HCV co-infection.
  • The findings highlight a significant public health concern regarding HIV/HCV co-infection.
Abstract

More Related Videos

Two Methods of Heterokaryon Formation to Discover HCV Restriction Factors16:49

Two Methods of Heterokaryon Formation to Discover HCV Restriction Factors

Published on: July 16, 2012

An In vitro Co-infection Model to Study Plasmodium falciparum-HIV-1 Interactions in Human Primary Monocyte-derived Immune Cells07:39

An In vitro Co-infection Model to Study Plasmodium falciparum-HIV-1 Interactions in Human Primary Monocyte-derived Immune Cells

Published on: August 15, 2012

Related Concept Videos

Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
Retrovirus Life Cycles01:10

Retrovirus Life Cycles

Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the retrovirus to...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...