[Computer morphometry of peripheral blood cells in patients of different age with pneumonia]

The aim of the research was to study blood responses to pneumonia in patients of different age and sex. The subjects of the study were 116 patients with extrahospital bacterial pneumonia (80 men and 36 women). The patients were divided into three age groups: 18 to 44 years, 45 to 59 years, and 60 to 74 years. Almost healthy 16 men and almost healthy 14 women have made the control groups. Computer morphometry of leukocytes of peripheral blood was made to all patients. Various reaction of lymphocytes on a pneumonia in men and women of young and middle age was revealed. Indirect evidences of decrease in level of lymphocytes activation in women of young and middle age at pneumonia development were received. The sizes of lymphocytes in elderly patients with pneumonia do not change comparing with the control groups. Sexual differences in reaction of monocytes to pneumonia are not present. The sizes of monocytes in patients with pneumonia of all age groups decrease at the expense of kernels, which indicate to their accelerated manufacture in a marrow. Absence of increase in cytoplasm to nucleus ratio index in elderly patients testifies a smaller degree of monocytes activation in this group of patients. The trend to reduction of the sizes of neutrophiles speaks of the accelerated division of predecessors' of mature neutrophiles. The increase in cytoplasm to nucleus ratio index of neutrophiles in women with pneumonia of young and middle age comparing with the control group specifies to the big degree of activation of neutrophiles link in these groups.