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[Lyell'a syndrome--two case presentations]
Justyna Kłos-Rola1, Jerzy Mackiewicz, Zbigniew Zagórski
1Katedra i Klinika Okulistyki, Uniwersytet Medyczny im. Feliksa Skubiszewskiego w Lublinie. jklosrola@gmail.com
Toxic epidermal necrosis (TEN) causes severe skin and mucous membrane damage, similar to extensive burns. Early and late-phase ophthalmic evaluation and treatment are crucial for managing ocular complications in TEN patients.
Area of Science:
- Dermatology
- Ophthalmology
- Critical Care Medicine
Background:
- Toxic epidermal necrosis (TEN) is a severe, life-threatening mucocutaneous reaction.
- Clinical manifestations include massive epidermolysis affecting skin and mucous membranes.
- Management often occurs in specialized burn or surgical centers.
Observation:
- Presents two case reports detailing ocular complications in patients with TEN.
- Highlights the significant impact of TEN on ocular structures.
- Underscores the potential for severe visual impairment.
Findings:
- Ocular complications are a significant concern in TEN patients.
- Timely ophthalmic intervention is necessary for both acute and chronic phases of TEN.
- Proactive eye care can mitigate long-term visual sequelae.
Implications:
- Emphasizes the critical role of ophthalmologists in the multidisciplinary care of TEN patients.
- Suggests integrating routine ophthalmic assessments into the standard management protocol for TEN.
- Advocates for early and continuous ophthalmologic monitoring to improve patient outcomes and prevent vision loss.
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