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Related Experiment Video

Updated: Jun 7, 2026

Bovine Mammary Gland Biopsy Techniques
14:53

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Published on: December 23, 2018

Mastitis and fertility disorders in cows.

E Malinowski1, Z Gajewski

  • 1Department of Pathophysiology of Reproduction and Mammary Gland, National Veterinary Research Institute in Puławy, Al. Powstańców Wlkp. 10, 85-090 Bydgoszcz, Poland. vetri@logonet.com.pl

Polish Journal of Veterinary Sciences
|November 2, 2010
PubMed
Summary

Mastitis negatively impacts cow fertility by altering blood and milk composition. Supportive treatments alongside intramammary therapy may improve fertility in affected cows.

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Area of Science:

  • Veterinary Medicine
  • Animal Reproduction
  • Biochemistry

Background:

  • Udder inflammation (mastitis) negatively affects cow reproductive efficiency, independent of milk yield or quality changes.
  • Mastitis alters milk and blood constituents, with pathogenic changes and new compounds impacting reproductive organs.
  • Fertility disorders in mastitic cows are linked to inflammatory mediators like cytokines (TNF-alpha), cortisol, prostaglandin F2-alpha, and reactive oxygen species (ROS).

Purpose of the Study:

  • To investigate the impact of mastitis on cow reproductive efficiency.
  • To explore the role of specific inflammatory mediators in mastitis-associated fertility issues.
  • To evaluate the efficacy of supportive drug injections in improving fertility in mastitic cows.

Main Methods:

  • Analysis of changes in milk and blood constituents during mastitis.
  • Monitoring of key inflammatory mediators (cytokines, cortisol, prostaglandins, ROS).
  • Clinical trials involving intramammary treatment combined with supportive drug injections (antioxidants, lysozyme dimer, flunixin meglumine).

Main Results:

  • Mastitis causes significant alterations in milk and blood, affecting the reproductive system.
  • Specific inflammatory mediators are identified as key factors in fertility disorders.
  • Supportive drug injections, when administered with intramammary treatments, showed potential to increase fertility in mastitic cows.

Conclusions:

  • Successful mastitis treatment and prevention are crucial for maintaining cow fertility.
  • Supportive therapies may offer a viable strategy to improve reproductive outcomes in cows suffering from mastitis.
  • Further research into supportive treatments could enhance prophylactic measures against fertility disorders in dairy herds.