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Related Experiment Video

Updated: Jun 7, 2026

Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pipientis for Genetic Drive

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Published on: July 4, 2007

Control of neglected tropical diseases needs a long-term commitment.

Yaobi Zhang¹, Chad MacArthur, Likezo Mubila

¹Helen Keller International, Regional Office for Africa, Dakar, Senegal. yzhang@hki.org

|November 2, 2010

Summary

Global efforts to control neglected tropical diseases (NTDs) show success, but require sustained funding and integrated healthcare systems for long-term impact. Continued collaboration is key to reaching all 2 billion affected individuals.

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Building a Better Mosquito: Identifying the Genes Enabling Malaria and Dengue Fever Resistance in A. gambiae and A. aegypti Mosquitoes

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Published on: July 4, 2007

Area of Science:

Global Health
Infectious Diseases
Public Health Policy

Background:

Neglected tropical diseases (NTDs) affect over 2 billion people, predominantly in sub-Saharan Africa.
Recent control efforts focus on five major NTDs (lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminthiasis, and trachoma) using integrated drug delivery.
Increased funding from governmental and non-governmental donors has accelerated disease control initiatives.

Purpose of the Study:

To evaluate the current landscape of NTD control strategies.
To identify key factors for achieving long-term sustainable control of NTDs.
To highlight the need for enhanced funding and coordinated efforts.

Main Methods:

Review of current NTD control programs and funding mechanisms.
Analysis of successful control strategies and contributing factors.
Assessment of the World Health Organization's guidelines for preventive chemotherapy.

Main Results:

Significant progress has been made in controlling several NTDs in endemic countries.
Current funding levels, while unprecedented, are insufficient to reach the entire affected population.
Integrated drug delivery and preventive chemotherapy are central to current control packages.

Conclusions:

Long-term sustainable NTD control requires sustained commitment from donors and endemic governments.
Strong partnerships between WHO, pharmaceutical industries, governments, communities, and NGOs are crucial.
Integrating NTD control into primary healthcare systems and strengthening these systems are vital for capacity building and program implementation.