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Updated: Jun 7, 2026

12:37
Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
Nutrition and melanoma prevention
J Daniel Jensen1, Gregory J Wing, Robert P Dellavalle
1Department of Dermatology, University of Colorado School of Medicine Denver, Aurora, CO, USA.
Clinics in Dermatology
|November 2, 2010
Summary
Dietary nutrients and botanicals show promise for melanoma chemoprevention, offering potential ways to protect against and reverse UV photodamage. Further research is needed to confirm their role in preventing skin cancer.
Area of Science:
- Oncology
- Dermatology
- Nutritional Science
Background:
- Melanoma incidence is increasing despite sun protection efforts.
- Sunscreen alone is insufficient for preventing UV-induced skin cancer.
- There is growing interest in dietary interventions for melanoma prevention.
Purpose of the Study:
- To review the literature on nutrition-related chemoprevention for melanoma.
- To explore the potential of dietary botanicals and vitamins in melanoma prevention.
Main Methods:
- Narrative review of nutrition-related literature.
- Searched PubMed using keywords: melanoma chemoprevention, nutrition and melanoma, dietary botanicals and melanoma prevention, green tea and melanoma, vitamin D and melanoma, vitamin E and melanoma.
Main Results:
- Basic science and epidemiological studies suggest potential benefits of natural products for melanoma chemoprevention.
- Evidence indicates promising roles for certain dietary factors.
Conclusions:
- While human randomized controlled trials are lacking, natural products show promise in basic science and epidemiological studies for melanoma chemoprevention.
- Future research should clarify the role of dietary nutrients in melanoma prevention.
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