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Updated: Jun 7, 2026

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling

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Published on: April 7, 2015

Post-streptococcal vasculopathy with evolution to Degos' disease.

Sandipan Pati¹, Suraj A Muley, Marie F Grill

¹Barrow Neurological Institute, 350 W Thomas Road, Phoenix, AZ 85013, United States. sandipan.pati@chw.edu

Journal of the Neurological Sciences

|November 2, 2010

Summary

Degos disease, a rare vascular condition, may be triggered by infections. This case report suggests a post-infectious immunologic mechanism may underlie malignant atrophic papulosis development.

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Area of Science:

Vascular Medicine
Immunology
Dermatology

Background:

Degos disease (malignant atrophic papulosis) is a rare occlusive vasculopathy with unknown etiology.
Proposed mechanisms include infections, autoimmune disorders, and coagulation defects, but lack confirmation.

Observation:

This report details a 41-year-old male patient diagnosed with Degos disease.
The patient experienced a streptococcal throat infection preceding the disease onset.

Findings:

Clinical, radiological, and histopathologic features of Degos disease were documented.
The case presents a potential link between streptococcal infection and the development of Degos disease.

Implications:

This case may provide further support for a post-infectious immunologic mechanism in Degos disease pathogenesis.
Further research into infection-triggered autoimmune responses could elucidate Degos disease etiology.