Related Experiment Video
Updated: Jun 7, 2026

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
Post-streptococcal vasculopathy with evolution to Degos' disease
Sandipan Pati1, Suraj A Muley, Marie F Grill
1Barrow Neurological Institute, 350 W Thomas Road, Phoenix, AZ 85013, United States. sandipan.pati@chw.edu
Abstract:
Degos' disease or malignant atrophic papulosis is a rare disseminated occlusive vasculopathy affecting the skin, gastrointestinal tract, central nervous system, and less often other organ systems. The exact etiology of this vasculopathy has not been established. Infections, autoimmune disease and coagulation defects have been proposed as underlying pathogenic mechanisms, but none have been confirmed. Here, we report the clinical, radiological and histopathologic features of Degos' disease in a 41-year-old man following streptococcal throat infection. Prior postulated hypothesis as post-infectious immunologic mechanism may be further supported by this case.
More Related Videos
Related Concept Videos
Rheumatic Heart Disease I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Streptococcal Pharyngitis
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Bacterial Meningitis II: Pathophysiology
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
