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Updated: Jun 7, 2026
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Behavioral Assessment of Hearing in 2 to 4 Year-old Children: A Two-interval, Observer-based Procedure Using Conditioned Play-based Responses
Published on: January 23, 2017
Study of auditory function in children with chronic lung diseases
Hanan M Ibrahim1, Terez B Kamel, Nithreen M S Abdel-Salam
1Pediatrics Department, Ain Shams University, Cairo, Egypt.
International Journal of Pediatric Otorhinolaryngology
|November 2, 2010
Summary
Children with chronic lung disease exposed to hypoxia show cochlear dysfunction. Otoacoustic emissions testing revealed hearing sensitivity issues, but inhaled aminoglycosides were found to be safe for auditory functions.
Area of Science:
- Pediatric Otolaryngology
- Pulmonology
- Audiology
Background:
- Chronic hypoxia significantly impacts cochlear function and hearing sensitivity.
- Otoacoustic emissions (OAEs) are effective for detecting subclinical cochlear impairment.
- Ototoxic drugs, such as aminoglycosides, are frequently used in managing chronic lung diseases.
Purpose of the Study:
- To evaluate cochlear function in children with chronic lung diseases.
- To assess the effects of prolonged hypoxia and inhaled aminoglycosides on auditory health.
- To utilize transient evoked otoacoustic emissions (TEOAEs) and basic audiological tests.
Main Methods:
- A cross-sectional study involving 30 Egyptian children with chronic lung disease.
- A control group of 20 healthy children was included.
- Audiological evaluation and TEOAEs were performed.
Main Results:
- Twenty percent (6/30) of children with chronic lung disease exhibited abnormal TEOAE findings.
- Prolonged hypoxia demonstrated a statistically significant impact on OAEs (P<0.05).
- No significant adverse effects of inhaled aminoglycosides were observed on pure tone audiometry, speech audiometry, or TEOAEs.
Conclusions:
- Children suffering from chronic lung diseases are at risk of cochlear dysfunction due to prolonged hypoxia.
- Inhaled aminoglycosides appear to be relatively safe concerning auditory functions in this patient group.
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