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Updated: Jun 7, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
Presurgical language fMRI activation correlates with postsurgical verbal memory decline in left-sided temporal lobe
Kirsten Labudda1, Markus Mertens, Joerg Aengenendt
1Mara Hospital, Bethel Epilepsy Center, Bielefeld, Germany.
Abstract:
We analysed the association of presurgical language fMRI activations and postsurgical verbal memory changes in 16 left-sided mesial temporal lobe epilepsy patients with initially intact memory. Patients with severe verbal memory decline after surgery (n = 9) had stronger presurgical fMRI activations within the left posterior temporal lobe, compared to those with no decline (n = 7). Language fMRI activation may predict verbal memory outcome, even in patients with a high risk of postsurgical memory deterioration.
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