Related Experiment Video
Updated: Jun 7, 2026
Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy
Published on: October 18, 2011
Lessons from a 17-year radiosurgery experience at the Royal Adelaide Hospital
Daniel E Roos1, Brian P Brophy, James Taylor
1Department of Radiation Oncology, School of Medicine, University of Adelaide, Royal Adelaide Hospital, Adelaide, South Australia. daniel.roos@health.sa.gov.au
Purpose:
To illustrate some of the potential pitfalls of cranial stereotactic radiosurgery (SRS) and its planning based on prospectively gathered data from a 17-year experience at the Royal Adelaide Hospital.
Methods And Materials:
More than 250 treatments have been planned since 1993 using previously described standard SRS techniques for intracranial benign and malignant lesions.
Results:
Five case studies are presented (1 meningioma, 1 acoustic neuroma, 2 solitary brain metastasis, 1 arteriovenous malformation), each of which demonstrates at least one salutary lesson.
Conclusions:
Because SRS delivers a highly conformal dose distribution, it is unforgiving of any geographic miss due to inaccurate outlining and thus dependent on neuroradiological expertise and collaboration. There are also potentially significant implications of misdiagnosis in SRS cases without histological proof--in particular, presumed brain metastases.
