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[Unusual presentation of scurvy mimicking a neuroblastoma]

S Rethore1, P Leblond, E Thebaud

  • 1Unité d'oncologie pédiatrique, centre Oscar-Lambret, 3 rue Frédéric-Combemale, Lille cedex, France.

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|November 2, 2010
PubMed

Insights

Scurvy, caused by ascorbic acid deficiency, is rare but can mimic serious conditions. This case highlights how scurvy can present with increased urinary catecholamines, mimicking neuroblastoma in children.

Area of Science:

  • Pediatric Medicine
  • Biochemistry
  • Oncology

Background:

  • Scurvy, a condition linked to ascorbic acid (vitamin C) deficiency, is uncommon in developed nations.
  • Ascorbic acid is crucial for collagen synthesis and catecholamine production.
  • Early diagnosis of scurvy is vital to prevent severe complications.

Observation:

  • A 2-year-old boy presented with pain and elevated urinary catecholamine levels.
  • These symptoms in a pediatric oncology unit raised suspicion for neuroblastoma.
  • The patient's presentation was unusual for typical scurvy cases.

Findings:

  • The unusual presentation was ultimately diagnosed as scurvy.
  • Ascorbic acid deficiency can lead to increased urinary catecholamine levels.
  • This diagnostic challenge underscores the importance of considering metabolic disorders.

Implications:

  • Physicians should consider scurvy in the differential diagnosis of pediatric pain and elevated catecholamines.
  • This case emphasizes the need for comprehensive metabolic evaluation in pediatric oncology.
  • Recognizing atypical scurvy presentations can prevent misdiagnosis and delayed treatment.

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