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Related Experiment Video

Updated: Jun 7, 2026

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

Indian genetic disease database.

Sanchari Pradhan¹, Mainak Sengupta, Anirban Dutta

¹Structural Biology and Bioinformatics Division, Indian Institute of Chemical Biology, Unit of CSIR, Kolkata, India.

Nucleic Acids Research

|November 2, 2010

Summary

This summary is machine-generated.

The Indian Genetic Disease Database (IGDD) provides comprehensive genetic mutation data for common diseases in India. This new resource aids researchers and clinicians in understanding and managing genetic disorders within Indian populations.

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Area of Science:

Genetics
Bioinformatics
Population Health

Background:

Indians comprise a significant global population with numerous endogamous groups.
High prevalence of recessive genetic diseases is observed in these groups.
A comprehensive database for Indian genetic diseases was lacking.

Purpose of the Study:

To develop and present the Indian Genetic Disease Database (IGDD) release 1.0.
To create an integrated and curated repository of mutation data for Indian populations.
To facilitate research and clinical management of genetic disorders in India.

Main Methods:

Compilation of mutation data from published literature.
Curation of information on 52 common genetic diseases and 5760 individuals.
Development of a searchable web portal with user-friendly interfaces.

Main Results:

The IGDD release 1.0 is now available online.
Database includes data on locus heterogeneity, mutation types, clinical and biochemical details, and geographical distribution.
Searchable by disease, gene, mutation type, and location.

Conclusions:

The IGDD is a valuable resource for geneticists, clinicians, and biologists.
It provides crucial information for understanding genetic diseases in Indian populations.
The database is designed for future data deposition and regular updates.