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Standardized Histomorphometric Evaluation of Osteoarthritis in a Surgical Mouse Model
Published on: May 6, 2020
Osteoarthritis: Small studies overestimate the benefit of therapies for OA
1Division of Rheumatology, University Hospitals of Geneva, Avenue Beau-Séjour 26, CH-1211 Geneva 14, Switzerland. A. Finckhaxel.finckh@hcuge.ch
Nature Reviews. Rheumatology
|November 2, 2010
Abstract:
a meta-epidemiological study has revealed that the inclusion of small studies in meta-analyses of osteoarthritis interventions could lead to an overestimation of the benefit of these interventions. Does this mean meta-analyses should be restricted to trials with large sample sizes?