Costs and benefits of free medications after myocardial infarction

Irfan A Dhalla1, Monique A Smith, Niteesh K Choudhry

  • 1Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Departments of Medicine and Health Policy, Management and Evaluation, University of Toronto, Toronto, ON.

Insights

Providing free secondary prevention medications to uninsured myocardial infarction patients significantly improves health outcomes and is cost-effective. This strategy enhances quality-adjusted life-years (QALYs) for patients and the healthcare system.

Area of Science:

  • Health Economics
  • Cardiovascular Medicine
  • Public Health Policy

Background:

  • Medication non-adherence after myocardial infarction (MI) limits the benefits of secondary prevention.
  • Financial barriers are a key driver of non-adherence.
  • This study assesses the economic impact of providing free medications to uninsured MI patients.

Purpose of the Study:

  • To evaluate the cost-effectiveness of full public coverage for secondary prevention medications for MI patients lacking private insurance.
  • To compare this intervention against the current healthcare system (status quo).

Main Methods:

  • Economic evaluation using decision analysis and Markov modelling.
  • Utilized Canadian data for cost and benefit estimations.
  • Primary outcome: incremental cost-effectiveness ratio (ICER) in cost per quality-adjusted life-year (QALY) gained.

Main Results:

  • Full public coverage increased QALYs (7.02 vs. 6.13) and healthcare costs ($20,423 vs. $17,173) compared to the status quo.
  • The ICER for full coverage was $3,663/QALY from the healthcare system perspective, robust under sensitivity analyses.
  • From a government perspective, the ICER was $12,350/QALY, sensitive to price elasticity but generally favorable.

Conclusions:

  • Full public coverage of secondary prevention medications is a cost-effective strategy for uninsured MI patients in Canada.
  • Public payers should consider implementing free medication programs to improve patient outcomes and reduce long-term healthcare burdens.
Abstract

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