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Rectal fluconazole for tinea capitis.

Jeffrey M Pernica1, Natalie Dayneka, Charles Ps Hui

  • 1Division of Infectious Diseases, Department of Paediatrics;

Paediatrics & Child Health
|November 2, 2010
PubMed
Summary
This summary is machine-generated.

Rectal fluconazole effectively treated tinea capitis in a child with autism spectrum disorder who refused oral medications. This rectal antifungal approach offered an excellent clinical outcome when oral and other rectal therapies failed.

Keywords:
Child developmental disordersFluconazolePervasiveTinea capitis

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Area of Science:

  • Dermatology
  • Pediatrics
  • Pharmacology

Background:

  • Tinea capitis is a common pediatric fungal infection.
  • Autistic children often exhibit medication aversion, complicating treatment.
  • Standard oral antifungal therapies may be challenging for these patients.

Observation:

  • A pediatric case of tinea capitis is presented in a boy with autistic spectrum disorder.
  • The patient demonstrated significant aversion to oral medications.
  • Previous treatments included refusal of oral fluconazole and poor response to rectal griseofulvin.

Findings:

  • Once-weekly rectal administration of fluconazole (10 mg/kg) was well-tolerated.
  • This rectal antifungal regimen resulted in an excellent clinical outcome for tinea capitis.
  • Rectal administration offers a viable alternative for antifungal therapy in non-compliant pediatric patients.

Implications:

  • Rectal fluconazole is a potential alternative for treating tinea capitis in pediatric patients with medication aversion.
  • This case highlights the importance of exploring alternative drug delivery routes for challenging pediatric populations.
  • Further research into the efficacy and tolerability of rectal antifungal formulations is warranted.