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Updated: Jun 7, 2026

Ultrasonographic Evaluation of Breast Cancer-related Lymphedema
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Breast elastography: a hospital-based preliminary study in China.

Shyam S Parajuly1, Peng Yu Lan, Luo Yan

  • 1Department of Diagnostic Ultrasound and The National Key Discipline of Medical Imaging and Nuclear Medicine, West China Hospital of Sichuan University, China.

Asian Pacific Journal of Cancer Prevention : APJCP
|November 3, 2010
PubMed
Summary

Ultrasound elastography significantly improves breast cancer detection accuracy compared to traditional B-mode sonography. This advanced imaging technique offers higher sensitivity and specificity for characterizing breast lesions, aiding in earlier diagnosis.

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Area of Science:

  • Radiology
  • Medical Imaging
  • Oncology

Background:

  • Breast cancer diagnosis relies heavily on imaging techniques.
  • B-mode sonography is a standard tool, but its accuracy in characterizing lesions can be limited.
  • Ultrasound elastography offers a complementary method to assess tissue stiffness, potentially improving diagnostic performance.

Purpose of the Study:

  • To evaluate the diagnostic performance of ultrasound elastography (UE) in characterizing breast lesions.
  • To compare the accuracy of UE with conventional B-mode sonography.
  • To assess the combined utility of UE and B-mode sonography for breast cancer detection.

Main Methods:

  • A study involving 150 patients with 170 breast lesions was conducted.
  • Lesions were classified using the BI-RADS lexicon and Ueno elastography scores.

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  • Histological correlation was used as the gold standard for diagnosis.
  • Main Results:

    • Ultrasound elastography demonstrated superior accuracy (95.8%) compared to B-mode sonography (90.6%).
    • UE showed higher sensitivity (98.6%) and specificity (96.0%) than B-mode sonography.
    • Combined use of sonography and UE improved sensitivity (98.57%) and reduced the false discovery rate.

    Conclusions:

    • Ultrasound elastography is a more effective tool than B-mode sonography for assessing the nature of breast lesions.
    • UE enhances diagnostic accuracy, sensitivity, and specificity in breast cancer characterization.
    • The combined application of sonography and UE offers improved diagnostic capabilities.