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Related Concept Videos

Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...

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Related Experiment Video

Updated: Jun 7, 2026

High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping
10:12

High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping

Published on: June 29, 2018

Genomic resources for flatfish research and their applications.

J Cerdà1, S Douglas, M Reith

  • 1Laboratory of Institut de Recerca i Tecnologia Agroalimentàries (IRTA) - Institut de Ciències del Mar, Consejo Superior de Investigaciones Científicas (CSIC), Passeig marítim 37-49, 08003 Barcelona, Spain. joan.cerda@irta.cat

Journal of Fish Biology
|November 3, 2010
PubMed
Summary

Functional genomics and

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Last Updated: Jun 7, 2026

High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping
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High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping

Published on: June 29, 2018

A Manual Small Molecule Screen Approaching High-throughput Using Zebrafish Embryos
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A Manual Small Molecule Screen Approaching High-throughput Using Zebrafish Embryos

Published on: November 8, 2014

Manipulation of Gene Function in Mexican Cavefish
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Published on: April 22, 2019

Area of Science:

  • Marine Biology
  • Genomics
  • Fisheries Science

Background:

  • Flatfishes are commercially important teleosts with complex, poorly understood biology.
  • Advancements in 'omic' technologies are beginning to illuminate their genetic underpinnings.

Purpose of the Study:

  • To review available functional genomic approaches and resources for flatfish research.
  • To summarize applications of microarray-based gene expression analysis in flatfishes.
  • To highlight the utility of genetic linkage maps for understanding genome organization and identifying commercially valuable traits.

Main Methods:

  • Review of existing literature on functional genomics in flatfishes.
  • Analysis of microarray data applications.
  • Examination of genetic linkage map construction and utility.

Main Results:

  • Functional genomic tools and resources are expanding, aiding flatfish research.
  • Microarray analyses have been applied across various flatfish research areas.
  • Genome sequencing data enables genetic map construction, crucial for trait identification.

Conclusions:

  • Genomic resources for flatfishes remain limited, necessitating further development.
  • Enhanced genomic databases, high-density microarrays, and detailed linkage maps are critical.
  • These tools will advance understanding of flatfish physiology, aiding conservation, welfare, and aquaculture.