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Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps
Published on: February 9, 2017
Analyzing temporal variability of standard descriptors of Poincaré plots
Chandan K Karmakar1, Jayavardhana Gubbi, Ahsan H Khandoker
1ISSNIP, Department of Electrical and Electronic Engineering, The University of Melbourne, VIC, Australia.
Abstract:
The Poincaré map is a visual technique to recognize the hidden correlation patterns of a time series signal. The standard descriptors of the Poincaré map are used to quantify the plot that measures the gross variability of the time series data. However, the problem lies in capturing temporal information of the plot quantitatively. In this article, we propose a new formulation for calculating the standard descriptors SD1 and SD2 from localized measures SD1^(w) and SD2^(w). To justify the importance of the temporal measure, SD1^(w), SD2^(w) are calculated for the 2 case studies (normal sinus rhythm [NSR] vs congestive heart failure and NSR vs arrhythmia) and are compared with the performance using the overall measures (SD1, SD2). Using overall SD1, receiver operating characteristic areas of 0.72 and 0.86 were obtained for NSR vs congestive heart failure and NSR vs arrhythmia, and using the proposed method resulted in 0.82 and 0.89. Because we have shown that the overall SD1 and SD2 are functions of the respective localized measures SD1^(w) and SD2^(w), we can conclude that use of localized measure provides equal or higher performance in pathology detection compared with the overall SD1 or SD2.
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