Related Experiment Video
Updated: Jun 7, 2026

19:57
An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
Published on: March 30, 2014
Behavioural interventions to reduce HIV risk: what works?
1Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, UK. david.ross@lshtm.ac.uk
AIDS (London, England)
|November 3, 2010
Summary
Reviewing HIV prevention strategies, this study found limited evidence of effectiveness from behavioral randomized trials. Future research should focus on reducing transmission and acquisition, considering sexual norms and condom use.
Area of Science:
- Public Health
- Epidemiology
- Behavioral Science
Background:
- HIV prevention efforts have focused on reducing risky sexual behaviors.
- Understanding the effectiveness of various intervention approaches is crucial for public health programming.
Purpose of the Study:
- To review HIV prevention intervention approaches.
- To summarize evidence on their effectiveness, particularly from randomized trials.
- To discuss future research and program directions.
Main Methods:
- Updated a recent systematic review of HIV prevention interventions.
- Focused on trials with HIV as a primary outcome.
Main Results:
- Five intervention approaches were identified: community-wide education, adolescent programs, high-risk group interventions, HIV testing/counseling, and interventions for HIV-positive individuals.
- None of the nine behavioral randomized trials with HIV outcomes demonstrated a significant impact.
- Limitations in trial design (e.g., sample size, coverage) and potential biases in behavioral outcome trials were noted.
Conclusions:
- Future research and programs need to prioritize interventions reducing both HIV transmission and acquisition.
- Emphasis should be placed on broader societal sexual norms, concurrency, and increasing condom acceptance and use.
Related Concept Videos
Retrovirus Life Cycles
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the retrovirus to...
Sexually Transmitted Infections
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Healthcare Associated Infections II: Preventive Measures
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Hand hygiene
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
Operant Conditioning Intervention
Operant conditioning serves as a foundational principle in therapeutic interventions aimed at modifying maladaptive behaviors. Central to this approach is the notion that behaviors, both adaptive and maladaptive, are learned through reinforcement. By analyzing the environmental factors that reinforce problematic behaviors, clinicians can design interventions to weaken these reinforcements and replace maladaptive behaviors with healthier alternatives.
In operant conditioning, behaviors that are...
In operant conditioning, behaviors that are...

