Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices01:28

Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

Parenteral drug delivery systems play a crucial role in modern therapeutics by enabling the direct administration of drugs into the systemic circulation, bypassing the gastrointestinal tract. These systems are particularly valuable for poorly absorbed oral medications that are unstable in the digestive environment or require rapid onset or sustained therapeutic levels. Delivery is achieved through intravenous, intramuscular, or subcutaneous routes, each selected based on the drug's properties...
Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
Routes of Drug Administration: Parenteral01:25

Routes of Drug Administration: Parenteral

The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability because the medication bypasses the harsh conditions of the gastrointestinal tract and hepatic metabolism.
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
Drug Products: Biologics, Biosimilars and Interchangeables01:28

Drug Products: Biologics, Biosimilars and Interchangeables

Biologics, derived from living sources such as humans, animals, or microorganisms, represent a significant category of pharmaceuticals. These complex molecules, developed through advanced biotechnological methods or purified from natural sources, include essential medical treatments like insulin and growth hormones. The complexity of biologics arises from their large molecular structures and the intricate processes required for their production, making them distinct from conventional...
Drug Dosage Regimen: Overview01:15

Drug Dosage Regimen: Overview

A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Drug Delivery: Miscellaneous Routes01:22

Drug Delivery: Miscellaneous Routes

Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs through the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

UK Vessel Health and Preservation (VHP) Framework: a commentary on the updated VHP 2020.

Journal of infection prevention·2021
Same author

Infusion medication concentrations in UK's critical care areas: Are the Intensive Care Society's recommendations being used?

Journal of the Intensive Care Society·2017
Same author

A NATIONAL SURVEY TO IDENTIFY HOW DISPLACEMENT VALUE INFORMATION IS USED AND PRESENTED TO CLINICAL STAFF IN NHS HOSPITALS.

Archives of disease in childhood·2016
Same author

How to remove a pulmonary artery catheter.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2016
Same author

Erlotinib and gefitinib for treating non-small cell lung cancer that has progressed following prior chemotherapy (review of NICE technology appraisals 162 and 175): a systematic review and economic evaluation.

Health technology assessment (Winchester, England)·2015
Same author

Genetic polymorphisms of heme-oxygenase 1 (HO-1) may impact on acute kidney injury, bronchopulmonary dysplasia, and mortality in premature infants.

Pediatric research·2015

Related Experiment Video

Updated: Jun 7, 2026

The Quantification of Injectability by Mechanical Testing
04:46

The Quantification of Injectability by Mechanical Testing

Published on: May 13, 2020

The Injectable Medicines Guide Website.

Susan Keeling1, Robin Burfield, Christine Proudlove

  • 1Pharmacy Department, Imperial College Healthcare NHS Trust.

British Journal of Nursing (Mark Allen Publishing)
|November 3, 2010
PubMed
Summary

The Injectable Medicines Guide website standardizes intravenous medicine administration information, addressing duplication of hospital guidelines. It offers tailored content and links to local resources for safer medication practices.

Area of Science:

  • Pharmaceutical Sciences
  • Health Informatics
  • Patient Safety

Background:

  • National Patient Safety Agency Alert 20 (2007) mandates point-of-care information for injectable medicine preparation and administration.
  • Historical development of local hospital guidelines led to significant duplication of effort.
  • A need existed for standardized, accessible information on intravenous (IV) medicine administration.

Purpose of the Study:

  • To describe the development of the Injectable Medicines Guide website.
  • To provide a standardized resource for intravenous medicine administration information.
  • To address the requirements of National Patient Safety Agency Alert 20.

Main Methods:

  • Development of a national website through collaboration with UK hospitals.

More Related Videos

Intramuscular Injections Along the Motor End Plates: A Minimally Invasive Approach to Shuttle Tracers Directly into Motor Neurons
10:57

Intramuscular Injections Along the Motor End Plates: A Minimally Invasive Approach to Shuttle Tracers Directly into Motor Neurons

Published on: July 13, 2015

Related Experiment Videos

Last Updated: Jun 7, 2026

The Quantification of Injectability by Mechanical Testing
04:46

The Quantification of Injectability by Mechanical Testing

Published on: May 13, 2020

Intramuscular Injections Along the Motor End Plates: A Minimally Invasive Approach to Shuttle Tracers Directly into Motor Neurons
10:57

Intramuscular Injections Along the Motor End Plates: A Minimally Invasive Approach to Shuttle Tracers Directly into Motor Neurons

Published on: July 13, 2015

  • Standardization of information on intravenous (IV) medicine administration.
  • Incorporation of features for local tailoring and linking of external guidelines.
  • Main Results:

    • The Injectable Medicines Guide website provides standardized IV medicine administration information.
    • The website allows for local customization and integration of local guidelines.
    • Updates are planned to include standard concentrations for critical care medications and intramuscular (IM) injection monographs for mental health.

    Conclusions:

    • The Injectable Medicines Guide website offers a standardized solution for injectable medicine information at the point of care.
    • The website's potential for universal access and integration with prescribing systems is hindered by a lack of robust funding.
    • Further funding is required to eliminate password protection and facilitate wider adoption across the UK.