Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 7, 2026

Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas
10:43

Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas

Published on: July 21, 2023

Single-strand DNA detection using a planar photonic-crystal-waveguide-based sensor.

V Toccafondo1, J García-Rupérez, M J Bañuls

  • 1Nanophotonics Technology Center, Universidad Politécnica de Valencia, Camino de Vera s/n, 46022 Valencia, Spain. vertocca@ntc.upv.es

Optics Letters
|November 3, 2010
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Experimental study of subwavelength grating bimodal waveguides as ultrasensitive interferometric sensors.

Optics letters·2019
Same author

Synchronization of Optomechanical Nanobeams by Mechanical Interaction.

Physical review letters·2019
Same author

Single-channel bimodal interferometric sensor using subwavelength structures.

Optics express·2019
Same author

Detection of sulphathiazole in honey samples using a lateral flow immunoassay.

Food chemistry·2019
Same author

Nanocrystalline silicon optomechanical cavities.

Optics express·2018
Same author

A self-stabilized coherent phonon source driven by optical forces.

Scientific reports·2015
Same journal

Gaussian-modulated continuous-variable quantum key distribution over 60 km fiber using an integrated silicon photonic receiver.

Optics letters·2026
Same journal

E2E-OCT: end-to-end joint learning model using optical coherence tomography images for vocal cord leukoplakia diagnosis.

Optics letters·2026
Same journal

Holographic generation of panoramic 3D scenes by concave ellipsoidal mirror reflection.

Optics letters·2026
Same journal

Dual-pilot phase recovery with pair-wise maximum-ratio combining for coherent PONs.

Optics letters·2026
Same journal

Mapping the whispering gallery modes of a CaF<sub>2</sub> disk resonator with half-tapered fibers to estimate the fundamental mode volume.

Optics letters·2026
Same journal

Quantitative estimation of deep-subwavelength scale via dark-field scattering axial energy concentration decay profiles.

Optics letters·2026
See all related articles

We demonstrated room temperature single-strand DNA (ssDNA) detection using a photonic-crystal optical sensor. This method achieved a 19.8 nM detection limit for complementary DNA strands.

Area of Science:

  • Optoelectronics
  • Biotechnology
  • Nanotechnology

Background:

  • Optical sensors offer label-free detection methods.
  • Photonic crystals provide unique light manipulation properties.
  • Single-strand DNA (ssDNA) detection is crucial for diagnostics.

Purpose of the Study:

  • To demonstrate ssDNA detection at room temperature.
  • To utilize a photonic-crystal-waveguide-based optical sensor.
  • To establish the detection limit for complementary DNA strands.

Main Methods:

  • Biofunctionalization of the sensor surface with ssDNA probes.
  • Utilizing planar photonic-crystal structures for detection.
  • Experimental measurement of hybridization events.

More Related Videos

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
08:59

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Published on: September 27, 2019

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor
07:28

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

Published on: August 30, 2012

Related Experiment Videos

Last Updated: Jun 7, 2026

Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas
10:43

Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas

Published on: July 21, 2023

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
08:59

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Published on: September 27, 2019

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor
07:28

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

Published on: August 30, 2012

Main Results:

  • Successful experimental demonstration of ssDNA detection.
  • Detection achieved at room temperature.
  • An estimated detection limit of 19.8 nM for complementary DNA strands was reached.

Conclusions:

  • Photonic-crystal-waveguide sensors are effective for ssDNA detection.
  • Room temperature operation is feasible.
  • The sensor shows promise for sensitive DNA analysis.