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Vascular abnormalities correlate with decreased soft tissue volumes in idiopathic clubfoot

Laura J Merrill1, Christina A Gurnett, Marilyn Siegel

  • 1Department of Orthopedic Surgery, Washington University School of Medicine, 1 Children's Place, Suite 4S60, St Louis, MO 63110, USA.

Clinical Orthopaedics and Related Research
|November 3, 2010
PubMed

Insights

This study found frequent vascular and soft tissue abnormalities in children with clubfoot. These findings, including reduced muscle and fat, were also present in recurrent clubfoot cases.

Area of Science:

  • Pediatric Orthopedics
  • Medical Imaging
  • Vascular Biology

Background:

  • Clubfoot is associated with lower extremity vascular anomalies, but soft tissue effects (fat, muscle) are understudied.
  • Safer, noninvasive imaging methods are needed for pediatric patients.

Purpose of the Study:

  • To describe a novel noninvasive imaging protocol for lower limb vascular and soft tissue abnormalities in clubfoot.
  • To determine if these abnormalities are more prevalent in recurrent clubfoot cases.

Main Methods:

  • Utilized 3D noncontrast-enhanced MR angiography.
  • Assessed vascular, bone, and soft tissue structures in clubfoot patients.
  • Compared abnormality frequency between isolated and recurrent clubfoot.

Main Results:

  • Identified arterial anomalies in the affected limb of unilateral clubfoot patients.
  • All patients showed reduced muscle volume; 82% had reduced subcutaneous fat.
  • Vascular anomalies and decreased fat/muscle volumes were observed in all recurrent clubfoot patients.

Conclusions:

  • High frequency of vascular and soft tissue anomalies in unilateral clubfoot limbs.
  • These anomalies may correlate with treatment response.
  • Noninvasive imaging effectively identifies these abnormalities.
Abstract

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