Total aortic arch replacement under intermittent pressure-augmented retrograde cerebral perfusion
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Updated: Jun 7, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Hiroshi Kubota1, Kunihiko Tonari, Hidehito Endo
1Department of Cardiovascular Surgery, Kyorin University, Tokyo, Japan. kub@ks.kyorin-u.ac.jp
Abstract:
Kitahori, Kawata, Takamoto et al. described the effectiveness of a novel protocol for retrograde cerebral perfusion that included intermittent pressure augmentation for brain protection in a canine model. Based on their report, we applied this novel technique clinically. Although the duration of circulatory arrest with retrograde cerebral perfusion was long, the patient recovered consciousness soon after the operation and had no neurological deficit. Near-infrared oximetry showed recovery of intracranial blood oxygen saturation every time the pressure was augmented.