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Updated: Jun 7, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

[Coding processes and executive functions in multiple sclerosis].

Isabel Introzzi¹, Sebastián Urquijo, María Fernanda López Ramón

¹Universidad Nacional de Mar de Plata/CONICET (Argentina), Facultad de Psicología, Mar del Plata, Argentina. isaintrozzi@hotmail.com

|November 4, 2010

Summary

Multiple sclerosis (MS) patients show impaired memory coding processes, linked to executive functioning deficits. This study highlights coding as a key area affected in MS memory loss.

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Published on: February 19, 2021

Area of Science:

Neuropsychology
Cognitive Neuroscience
Neurology

Context:

Episodic memory deficits are common in multiple sclerosis (MS).
The cognitive origins of MS-related memory impairment are debated, with theories focusing on memory retrieval versus encoding processes.
The relationship between memory coding and executive functions in MS is under-researched.

Purpose:

To investigate coding processes and their association with executive control functions in individuals with multiple sclerosis (MS).
To evaluate coding abilities using specific indices from the Test of Verbal Learning (TAVEC).
To assess executive functions through semantic verbal fluency, the Wisconsin Card Sorting Test (WCST), and WAIS III matrix reasoning.

Summary:

This study examined 36 patients with MS and 36 matched healthy controls.
Results revealed significant deficits in memory coding processes among MS patients.
A notable association was found between impaired coding processes and executive functioning in the MS group.

Impact:

Identifies memory coding deficits as a significant factor contributing to memory impairment in multiple sclerosis (MS).
Suggests that executive functions play a crucial role in modulating memory coding in MS.
Provides a basis for developing targeted cognitive interventions for memory issues in MS patients.