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Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
Commonly used reporter...
Cell Specific Gene Expression01:58

Cell Specific Gene Expression

Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...
Cell Specific Gene Expression01:58

Cell Specific Gene Expression

Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...
What is Gene Expression?01:42

What is Gene Expression?

Overview
Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
Genetic Information Flows from DNA to RNA to Protein
A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is made up of nucleotides and proteins consist of amino...
What is Gene Expression?01:36

What is Gene Expression?

A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is comprised  of nucleotides and proteins are comprised of amino acids, a mediator is required to convert the information encoded in DNA into proteins. This mediator is the messenger RNA (mRNA). mRNA copies the blueprint from DNA by a process called transcription. In eukaryotes, transcription occurs in the nucleus by complementary base-pairing with the DNA template. The mRNA is then processed and...
What is Gene Expression?01:42

What is Gene Expression?

Overview
Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
Genetic Information Flows from DNA to RNA to Protein
A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is made up of nucleotides and proteins consist of amino...

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Related Experiment Video

Updated: Jun 7, 2026

Single Cell Analysis Of Transcriptionally Active Alleles By Single Molecule FISH
06:26

Single Cell Analysis Of Transcriptionally Active Alleles By Single Molecule FISH

Published on: September 20, 2020

Focus issue: signals for gene expression.

Wei Wong

    Science Signaling
    |November 4, 2010
    PubMed
    Summary

    This Science Signaling issue explores gene regulation, focusing on how signaling pathways influence epigenetic patterns and gene expression. It covers transcriptional networks and microRNA regulation of signaling molecules.

    Area of Science:

    • Molecular Biology
    • Genetics
    • Cell Signaling

    Background:

    • This issue focuses on gene regulatory events, complementing a special issue on epigenetics.
    • It highlights the intricate connections between signaling pathways and gene regulation.

    Discussion:

    • Explores how signaling pathways impact epigenetic patterning, influencing gene expression.
    • Details the organization of transcriptional networks and their role in gene regulation.
    • Examines the posttranscriptional regulation of signaling molecules by microRNAs (miRNAs).

    Key Insights:

    • Signaling pathways are crucial regulators of epigenetic modifications.
    • MicroRNAs play a significant role in controlling signaling molecule activity.
    • Understanding these regulatory mechanisms is key to deciphering gene expression control.

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    An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions
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    Related Experiment Videos

    Last Updated: Jun 7, 2026

    Single Cell Analysis Of Transcriptionally Active Alleles By Single Molecule FISH
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    Published on: September 20, 2020

    Quantification of Global Histone Post Translational Modifications Using Intranuclear Flow Cytometry in Isolated Mouse Brain Microglia
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    An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions
    07:59

    An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions

    Published on: March 22, 2018

    Outlook:

    • Future research directions in gene regulation and epigenetics.
    • Potential therapeutic targets based on signaling pathway and miRNA interactions.