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Related Concept Videos

Chest Physiotherapy01:24

Chest Physiotherapy

Chest Physiotherapy (CPT) is a therapeutic technique used in respiratory care to improve ventilation, clear bronchial secretions, and enhance the efficiency of respiratory muscles. This therapy includes three primary procedures: postural drainage, percussion, and vibration. It can be performed on spontaneously breathing patients and those who are intubated and mechanically ventilated.
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Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
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Related Experiment Video

Updated: Jun 7, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Bronchial thermoplasty for severe asthma.

Gerard Cox1

  • 1Firestone Institute for Respiratory Health, St Joseph's Healthcare, Hamilton, Ontario, Canada. coxp@mcmaster.ca

Current Opinion in Pulmonary Medicine
|November 4, 2010
PubMed
Summary

Bronchial thermoplasty offers a new treatment option for severe asthma, complementing traditional medications. Patient selection criteria are now established, with long-term studies showing persistent benefits and no late adverse events.

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Area of Science:

  • Pulmonology
  • Respiratory Medicine
  • Medical Devices

Background:

  • Severe asthma remains a challenge, often inadequately controlled by conventional therapies.
  • Bronchial thermoplasty (BT) is an endoscopic procedure delivering radiofrequency energy to the airways.

Purpose of the Study:

  • To evaluate the role of bronchial thermoplasty as an adjunct therapy for severe asthma.
  • To define patient selection criteria for optimizing BT outcomes.
  • To review long-term safety and efficacy data following BT.

Main Methods:

  • Review of recent studies on bronchial thermoplasty in severe asthma patients.
  • Analysis of patient selection criteria and treatment outcomes.
  • Assessment of long-term follow-up data for persistent benefits and adverse events.

Main Results:

  • Two recent studies demonstrate the utility of BT in severe asthma.
  • Experience now allows for better patient selection to maximize benefits and minimize risks.
  • Long-term follow-up confirms sustained benefits and the absence of late-onset complications.

Conclusions:

  • Bronchial thermoplasty is a novel, complementary treatment for asthma, alongside anti-inflammatory and bronchodilating medications.
  • Established criteria aid in appropriate patient selection for BT.
  • Expanding experience and FDA approval (since April 2010) support its growing role in asthma management.