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Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach
09:01

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach

Published on: January 24, 2018

Total knee replacement in patients with below-knee amputation.

Matthew D Karam1, Michael Willey, Donald G Shurr

  • 1The University of Iowa, Department of Orthopaedics and Rehabilitation, 200 Hawkins Drive, Iowa City, IA 52242, USA.

The Iowa Orthopaedic Journal
|November 4, 2010
PubMed
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Total knee replacement (TKR) can effectively treat severe arthritis in patients unresponsive to conservative measures. This study reviews TKR in transtibial amputation patients, presenting a case of contralateral TKR.

Area of Science:

  • Orthopedic Surgery
  • Biomedical Engineering
  • Rehabilitative Medicine

Background:

  • Total knee replacement (TKR) is a common procedure for severe knee arthritis unresponsive to conservative treatments.
  • Lower extremity amputations are frequent, with diabetes mellitus being a leading cause.
  • Transtibial amputation can lead to degenerative joint disease in the contralateral limb.

Observation:

  • There are limited documented cases of TKR in patients with a history of transtibial amputation.
  • Patients with transtibial amputation may have a higher risk of osteoarthritis in the opposite knee.
  • Radiographic evidence of osteoporosis is common in amputated limbs.

Findings:

  • This study reviews existing data on TKR in patients with transtibial amputation.

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Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
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Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

Published on: July 22, 2021

Related Experiment Videos

Last Updated: Jun 7, 2026

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach
09:01

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach

Published on: January 24, 2018

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
06:06

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

Published on: July 22, 2021

  • A case of contralateral TKR in a patient with a transtibial amputation is presented.
  • The safety and efficacy of TKR in this specific patient population require further investigation.

    • Implications:

    • Understanding the outcomes of TKR in patients with lower extremity amputation is crucial for surgical planning.
    • Further research is needed to establish best practices for managing knee arthritis in amputees.
    • This review aims to contribute to the limited existing literature on this complex orthopedic scenario.