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Updated: Jun 7, 2026

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus

Published on: January 17, 2025

Staphylococcus aureus infections in adolescents.

Blanca E Gonzalez¹, Rodrigo A Mon

¹Division of Pediatric Infectious Diseases and Rheumatology, Rainbow Babies and Children's Hospital, 11100 Euclid Avenue, Cleveland, OH 44106, USA. blanca.gonzalez@uhhospitals.org

Adolescent Medicine: State of the Art Reviews

|November 5, 2010

Summary

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is a growing threat to adolescents, causing infections from skin issues to sepsis. This review details CA-MRSA in teens, covering diagnosis, treatment, and prevention strategies.

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Last Updated: Jun 7, 2026

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus

Published on: January 17, 2025

Area of Science:

Pediatric infectious diseases
Adolescent health
Microbiology

Background:

Staphylococcus aureus infections contribute significantly to pediatric morbidity and mortality.
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has become a notable pathogen in adolescents.
Adolescent-specific conditions and behaviors increase susceptibility to staphylococcal infections.

Purpose of the Study:

To review the prevalence and impact of Staphylococcus aureus infections in the adolescent population.
To outline current approaches to the diagnosis and treatment of S. aureus infections in adolescents.
To discuss strategies for the prevention of S. aureus infections among adolescents.

Main Methods:

Literature review focusing on Staphylococcus aureus and CA-MRSA in adolescents.
Analysis of disease presentation, from skin and soft tissue infections to sepsis syndrome.
Synthesis of information on diagnostic, therapeutic, and preventive measures.

Main Results:

CA-MRSA infections in adolescents range from localized skin infections to severe systemic disease.
Adolescent lifestyles and physiological factors contribute to increased infection risk.
Effective management requires timely diagnosis and appropriate antimicrobial therapy.

Conclusions:

Staphylococcus aureus, particularly CA-MRSA, poses a significant health challenge for adolescents.
A comprehensive approach involving early detection, tailored treatment, and preventative education is crucial.
Further research into adolescent-specific risk factors and interventions is warranted.