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Updated: Jun 7, 2026

An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug
Published on: June 4, 2021
Interventional therapies for venous thromboembolism: vena caval interruption, surgical embolectomy, and
1Division of Pulmonary and Critical Care Medicine, Room 351, Bell Building, Box 31175, Duke University Medical Center, Durham, NC, 27710, USA. tapso001@mc.duke.edu
Abstract:
Therapeutic strategies other than anticoagulation sometimes require consideration in the setting of acute venous thromboembolism. Vena caval filter placement is increasingly common, in part because of the availability of nonpermanent filter devices. Filter placement, surgical embolectomy, and catheter embolectomy have not been subjected to the same prospective, randomized clinical trial scrutiny as anticoagulation but seem appropriate in certain clinical settings. The indications, contraindications, and available data supporting these therapeutic methods are discussed.
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