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Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

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Magnetic resonance spectroscopy in ring enhancing lesions.

R Seth¹, V Kalra, U Sharma

¹Department of Pediatrics, All India Institute of Medical Sciences, New Delhi 110 029, India. drrachnaseth@yahoo.co.in

Indian Pediatrics

|November 5, 2010

Summary

Magnetic resonance spectroscopy (MRS) aided in diagnosing brain tuberculoma in a child with ring-enhancing lesions. This imaging technique proved crucial when initial treatments for presumed neurocysticercosis failed, leading to successful antituberculosis therapy.

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Area of Science:

Neurology
Radiology
Infectious Diseases

Background:

Ring-enhancing lesions on brain imaging can present a diagnostic challenge.
Neurocysticercosis is a common differential diagnosis for such lesions, especially in endemic areas.
Treatment failure for presumed neurocysticercosis necessitates further diagnostic investigation.

Observation:

A 4-year-old girl presented with ring-enhancing lesions on computed tomography (CT).
Initial diagnosis was neurocysticercosis, but the patient did not respond to cysticidal therapy.
Magnetic resonance spectroscopy (MRS) was performed to further evaluate the lesions.

Findings:

MRS revealed characteristic lipid peaks, strongly suggesting intracranial tuberculoma.
The patient was treated with antituberculosis therapy based on the MRS findings.
The lesions showed successful resolution following antituberculosis treatment.

Implications:

This case underscores the utility of MRS in differentiating causes of ring-enhancing brain lesions.
MRS can guide appropriate therapy when initial diagnoses are uncertain or treatment is ineffective.
Early and accurate diagnosis of intracranial tuberculoma is vital for effective management and improved patient outcomes.