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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions01:24

Drug Accumulation During Multiple Dosing: Intermittent IV Infusions

Intermittent intravenous (IV) infusion is a method of drug administration where medications are delivered over short infusion periods followed by intervals of no drug delivery. This approach helps to prevent sustained high drug concentrations in the bloodstream, reducing the risk of adverse effects associated with prolonged exposure. Unlike continuous infusion, steady-state concentrations may not be achieved during a single dosing cycle but can be reached through repeated...

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Related Experiment Videos

Adherence to topical glaucoma medication during hospitalization.

Salman J Yousuf1, Leslie S Jones

  • 1Department of Ophthalmology, Howard University Hospital, Washington, District of Columbia.

Journal of Glaucoma
|November 5, 2010
PubMed
Summary

Glaucoma medication adherence was suboptimal in hospitalized patients, with over half not receiving adequate doses. Failure to prescribe and poor documentation of outpatient regimens contributed to this issue.

Related Experiment Videos

Area of Science:

  • Ophthalmology
  • Patient Care

Background:

  • Glaucoma management requires consistent topical medication adherence.
  • Hospitalization can disrupt established medication routines for chronic conditions like glaucoma.

Purpose of the Study:

  • To investigate adherence patterns to topical glaucoma medications during inpatient stays.
  • To identify factors predicting adherence in hospitalized glaucoma patients.

Main Methods:

  • Retrospective case-series analysis of 184 hospitalized patients with glaucoma.
  • Review of medical records to assess outpatient medication knowledge, inpatient prescription, and adherence (≥75% of doses).

Main Results:

  • Only 51.6% of patients achieved adherence to topical glaucoma medications.
  • Adherence was significantly associated with complete knowledge and prescription of outpatient regimens upon admission.
  • Failure to prescribe the outpatient regimen was the primary reason for omitted doses (72.3%).

Conclusions:

  • Topical glaucoma medication adherence is suboptimal during hospitalization, often due to poor medication reconciliation.
  • Improving the reporting and prescription of outpatient regimens is crucial for enhancing inpatient glaucoma care.
  • Hospitalization's impact on adherence warrants further investigation and consideration in post-discharge evaluations.