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Updated: Jun 7, 2026

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma
Published on: February 22, 2015
Glioblastoma multiforme of the cerebellum
Mohammad M Al-Barbarawi1, Suhair M Qudsieh, Mohamed A Ghazzawi
1Division of Neurosurgery, Department of Neuroscience, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan. Tel. +962 (79) 5080012. Fax. +962 (6) 5666259.
Abstract:
Glioblastoma multiforme (GBM) is a highly malignant glial tumor seen commonly in the cerebral hemispheres, but rarely encountered in the cerebellum. It may occur at any age, but is seen more often in adult age groups. Despite its rarity, GBM should be considered in patients with a ring-enhancing lesion in the cerebellum. No consensus regarding the best management has yet been established. However, multimodal treatment is currently available to deal with these lesions: wide excision with radiochemotherapy may improve and prolong the patients life. Although the outcome remains dismal, we emphasize that timely multi modal treatment may provide the patient a better outcome and longer life. Herein, we report 2 new cases of cerebellar GBM and discuss their outcome and present a review of the relevant literature.
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