Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
iPS Cell Differentiation01:22

iPS Cell Differentiation

The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
Adult Stem Cells01:33

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Progressive Success in Uterus Transplants-From Experimental to Clinical Reality.

JAMA surgery·2026
Same author

Production of Large Ellipsoidal Ablations Using Integrated Nanosecond Pulse Irreversible Electroporation Administered via a Single Applicator and Grounding Pad.

Journal of vascular and interventional radiology : JVIR·2026
Same author

Improved Outcomes with Hypothermic Machine Perfusion in Donation after Circulatory Death Liver Transplantation.

Journal of the American College of Surgeons·2026
Same author

Integrated Nanosecond Pulse Irreversible Electroporation (INSPIRE): Impact of Exposed Electrode Length on Ablation Geometry in an In Vivo Liver Model.

Cancers·2025
Same author

Dose Is a Critical Factor Affecting Treatment Volumes for Integrated Nanosecond Pulse Irreversible Electroporation (INSPIRE).

IEEE transactions on bio-medical engineering·2025
Same author

Construction of functional tissue-engineered microvasculatures using circulating fibrocytes as mural cells.

Journal of tissue engineering·2025
Same journal

RETRACTION: The DNMT1/miR-34a Axis Is Involved in the Stemness of Human Osteosarcoma Cells and Derived Stem-Like Cells.

Stem cells international·2026
Same journal

RETRACTION: Uric Acid-Induced Adipocyte Dysfunction Is Attenuated by HO-1 Upregulation: Potential Role of Antioxidant Therapy to Target Obesity.

Stem cells international·2026
Same journal

In Vitro Evaluation of Mechanical Fat Processing Devices: Impact on Adipocytes and Adipose-Derived Stem Cells.

Stem cells international·2026
Same journal

Hyaluronic Acid Hydrogel Inhibits Autophagy Through the miR-181a-5p/ATG5 Molecular Axis to Promote the Adipogenic Differentiation of Adipose-Derived Stem Cells.

Stem cells international·2026
Same journal

RETRACTION: Naringin Stimulates Osteogenic Differentiation of Rat Bone Marrow Stromal Cells via Activation of the Notch Signaling Pathway.

Stem cells international·2026
Same journal

Efficient Derivation and Transcriptional Characterization of Mouse Extra-Embryonic Endoderm Stem Cell Lines Generated by Somatic Cell Nuclear Transfer.

Stem cells international·2026
See all related articles

Related Experiment Video

Updated: Jun 7, 2026

Isolation of Perivascular Multipotent Precursor Cell Populations from Human Cardiac Tissue
08:15

Isolation of Perivascular Multipotent Precursor Cell Populations from Human Cardiac Tissue

Published on: October 8, 2016

Tissue-derived stem and progenitor cells.

Leora J Tesche1, David A Gerber

  • 1Department of Surgery, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7211, USA.

Stem Cells International
|November 5, 2010
PubMed
Summary
This summary is machine-generated.

This review covers stem cell research, focusing on tissue-derived stem cells from the liver, central nervous system, and heart. It discusses research successes, challenges, and clinical therapy hurdles.

More Related Videos

Repair of a Critical-sized Calvarial Defect Model Using Adipose-derived Stromal Cells Harvested from Lipoaspirate
11:31

Repair of a Critical-sized Calvarial Defect Model Using Adipose-derived Stromal Cells Harvested from Lipoaspirate

Published on: October 31, 2012

Isolation of Blood-vessel-derived Multipotent Precursors from Human Skeletal Muscle
10:52

Isolation of Blood-vessel-derived Multipotent Precursors from Human Skeletal Muscle

Published on: August 21, 2014

Related Experiment Videos

Last Updated: Jun 7, 2026

Isolation of Perivascular Multipotent Precursor Cell Populations from Human Cardiac Tissue
08:15

Isolation of Perivascular Multipotent Precursor Cell Populations from Human Cardiac Tissue

Published on: October 8, 2016

Repair of a Critical-sized Calvarial Defect Model Using Adipose-derived Stromal Cells Harvested from Lipoaspirate
11:31

Repair of a Critical-sized Calvarial Defect Model Using Adipose-derived Stromal Cells Harvested from Lipoaspirate

Published on: October 31, 2012

Isolation of Blood-vessel-derived Multipotent Precursors from Human Skeletal Muscle
10:52

Isolation of Blood-vessel-derived Multipotent Precursors from Human Skeletal Muscle

Published on: August 21, 2014

Area of Science:

  • Stem cell biology and regenerative medicine.

Background:

  • Stem cell research has rapidly advanced with the isolation of diverse stem cell populations.
  • Identifying markers for specific stem cells aids in understanding their expression across different organs and tissues.

Purpose of the Study:

  • To review the current state of research on tissue-derived stem cells.
  • To highlight successes and challenges in isolating and characterizing stem cells from liver, central nervous system, and cardiac tissues.
  • To discuss the clinical therapy challenges associated with these stem cell populations.

Main Methods:

  • Literature review of scientific publications on stem cell research.
  • Analysis of marker expression in various tissue-derived stem cell populations.
  • Discussion of clinical applications and challenges.

Main Results:

  • Significant progress has been made in characterizing and isolating stem cells from various tissues.
  • Common markers are utilized to identify and differentiate stem cell populations across different organ systems.
  • Challenges remain in translating stem cell research into effective clinical therapies.

Conclusions:

  • Tissue-derived stem cells offer promising avenues for research and potential therapies.
  • Further research is needed to overcome challenges in stem cell isolation, characterization, and clinical application.
  • Understanding stem cell behavior in specific tissues is crucial for therapeutic development.