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Bronchopulmonary dysplasia as a predictor factor for motor alteration at 6 months corrected age in premature infants

Priscila Silveira Martins1, Rosane Reis de Mello, Kátia Silveira da Silva

  • 1Instituto Fernandes Figueira, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro RJ, Brazil.

Arquivos De Neuro-Psiquiatria
|November 5, 2010
PubMed

Insights

Bronchopulmonary dysplasia (BPD) independently increases the risk of psychomotor development issues in premature infants. This study found BPD is a significant factor for altered psychomotor development index at 6 months corrected age.

Area of Science:

  • Neonatal Medicine
  • Developmental Pediatrics
  • Pediatric Pulmonology

Background:

  • Premature infants face risks for neurodevelopmental deficits.
  • Bronchopulmonary dysplasia (BPD) is a common complication in very low birth weight (VLBW) infants.
  • Long-term neurodevelopmental outcomes in infants with BPD require further investigation.

Purpose of the Study:

  • To evaluate bronchopulmonary dysplasia (BPD) as a risk factor for psychomotor development index (PDI) alterations.
  • To determine the incidence of neuromotor alterations at 6 months corrected age in premature infants.
  • To identify the independent contribution of BPD to neurodevelopmental outcomes.

Main Methods:

  • Prospective cohort study design.
  • Inclusion of 152 very low birth weight premature infants.
  • Assessment of psychomotor development index using the Bayley Scale of Infant Development at 6 months corrected age.
  • Neurological examination for neuromotor assessment.

Main Results:

  • The incidence of BPD was 13.2% (20 out of 152 infants).
  • Bronchopulmonary dysplasia was associated with an altered psychomotor development index (OR 3.98; 95%CI: 1.04-15.1) after adjusting for confounders.
  • Neurological examinations revealed alterations in 67.1% of the infants.

Conclusions:

  • Bronchopulmonary dysplasia is an independent risk factor for altered psychomotor development in premature infants.
  • The findings highlight the significant impact of BPD on neurodevelopmental outcomes at 6 months corrected age.
  • Early identification and intervention for neurodevelopmental issues in infants with BPD are crucial.
Abstract

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