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Updated: Jun 7, 2026

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Published on: March 4, 2017
Congenital cutaneous candidiasis associated with respiratory distress in a full-term newborn
Faten Tinsa1, Khadija Boussetta, Dalel Ben Hassine
1Department of Pediatrics B, Children's Hospital of Tunis, Tunis, Tunisia.
Background:
Congenital candidiasis is rare occurring in most cases in premature and low birth weight new born. It can produce a spectrum of disease ranging from a diffuse skin eruption to a severe systemic disease with or without skin involvement. Amphotericin B is the first-line agent for the treatment of systemic disease.
Aim:
To describe a congenital candidiasis in a full-term newborn.
Case Report:
At birth, the newborn had a generalized, erythematous, papulovesicular eruption. He was treated by topic antifungal therapy. However, on the third day, he developed a systemic disease with respiratory distress and fever. Ear, skin swab and gastric aspirate grew to Candida albicans. The newborn was given fluconazole for 10 days with favourable outcome.
Conclusion:
Early topic therapy did not prevent systemic spread of congenital cutaneous candidiasis in our case. Treatment with fluconazole, as the first-line agent, seems effective and safe.
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