Related Experiment Video

Updated: Jun 7, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Translational research to prevent internalizing problems early in childhood

Jordana K Bayer1, Ronald M Rapee, Harriet Hiscock

  • 1Centre for Community Child Health, and 3Department of Paediatrics, The University of Melbourne, Parkville, VIC, Australia.

Depression and Anxiety
|November 5, 2010
PubMed

Insights

Early intervention for internalizing problems in preschoolers is crucial. Translational research is evaluating population-level screening and parenting interventions to prevent these issues effectively.

Area of Science:

  • Child Psychology
  • Developmental Psychiatry
  • Public Health

Background:

  • Internalizing problems affect 1 in 7 school-aged children, with significant long-term impacts.
  • The World Health Organisation (WHO) predicts a substantial global burden of internalizing problems by 2030.
  • Early childhood intervention shows cost-effective benefits for developmental outcomes compared to later interventions.

Purpose of the Study:

  • To discuss the importance of translational research for early prevention of child internalizing problems.
  • To describe an approach to translational effectiveness research for preschooler internalizing issues.
  • To address gaps in early childhood prevention strategies for internalizing disorders.

Main Methods:

  • Review of existing randomized "efficacy" trials of parenting group interventions for inhibited preschoolers.
  • Initiation of translational "effectiveness" research at the population level.
  • Systematic screening of preschoolers for inhibition and subsequent intervention evaluation.

Main Results:

  • Previous efficacy trials demonstrated that parenting interventions reduced internalizing disorders in preschoolers up to 3 years later.
  • Ongoing effectiveness research aims to determine the benefits and harms of population-level screening and intervention.
  • The research addresses critical needs identified by the WHO Prevention of Mental Disorders report.

Conclusions:

  • Early intervention during preschool years is vital for preventing internalizing problems.
  • Translational effectiveness research is essential to implement and scale up evidence-based interventions.
  • Systematic screening and targeted interventions can mitigate the impact of risk factors like temperamental inhibition and overinvolved parenting.

More Related Videos

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

Related Concept Videos

Relationship with Parents: Attachment01:28

Relationship with Parents: Attachment

Parent-child interactions lay the foundation for how we understand relationships throughout life. These interactions are not uniform across families; instead, they are shaped by a range of environmental, emotional, and behavioral factors unique to each caregiver-child dynamic. Social psychologists study these early relationships to understand how patterns formed in infancy influence social functioning and interpersonal behavior in adulthood.Attachment Theory and Early Relational ModelsJohn...
Socioemotional Development during Infancy01:30

Socioemotional Development during Infancy

Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
Primary Temperament Types
Stella Chess...
Information Processing Approach01:30

Information Processing Approach

The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is also...
Autism Spectrum Disorder01:19

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Conduct Disorder01:28

Conduct Disorder

Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...
Operant Conditioning Intervention01:24

Operant Conditioning Intervention

Operant conditioning serves as a foundational principle in therapeutic interventions aimed at modifying maladaptive behaviors. Central to this approach is the notion that behaviors, both adaptive and maladaptive, are learned through reinforcement. By analyzing the environmental factors that reinforce problematic behaviors, clinicians can design interventions to weaken these reinforcements and replace maladaptive behaviors with healthier alternatives.
In operant conditioning, behaviors that are...