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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Published on: June 2, 2014

Migraine: prophylactic treatment.

Rakesh Shukla1, Manish Sinh

  • 1Department of Neurology, CSM Medical University, Lucknow-226003, Uttar Pradesh.

The Journal of the Association of Physicians of India
|November 6, 2010
PubMed
Summary
This summary is machine-generated.

Effective migraine management involves lifestyle changes and medications. First-choice drugs include beta-blockers and topiramate, while second-choice options offer less evidence. Future treatments aim for greater efficacy based on pathophysiology.

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Area of Science:

  • Neurology
  • Pharmacology

Background:

  • Migraine prophylaxis is crucial for patient management.
  • Current strategies include lifestyle modifications and medication.

Purpose of the Study:

  • To review current prophylactic treatments for migraine.
  • To discuss the efficacy and limitations of available therapies.

Main Methods:

  • Literature review of first- and second-choice prophylactic migraine medications.
  • Evaluation of non-pharmacological interventions and emerging treatments.

Main Results:

  • First-choice drugs: beta-blockers, flunarizine, topiramate, valproate, amitriptyline.
  • Second-choice drugs: venlafaxine, gabapentin, naproxen, butterbur, riboflavin, magnesium.
  • Botulinum toxin type A lacks proven efficacy; non-pharmacological methods show some promise.

Conclusions:

  • Drug selection depends on efficacy, comorbidities, side effects, and cost.
  • Future migraine therapies may arise from a deeper understanding of pathophysiology.