Membrane-associated crystallization of calcium oxalate in vitro
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S R Khan1, P N Shevock, R L Hackett
1Department of Pathology, College of Medicine, University of Florida, Gainesville 22610.
Calcified Tissue International
|February 1, 1990
Abstract:
Incubation of proximal tubular brush border membrane in a metastable calcium oxalate solution of low supersaturation resulted in the equimolar depletion of calcium and oxalate and the formation of monoclinic calcium oxalate crystals. We propose that membrane fragments from sloughed epithelial cells of the nephron can similarly induce crystallization in urine that is metastable for calcium oxalate.