Related Experiment Video

Updated: Jun 7, 2026

Two Methods of Heterokaryon Formation to Discover HCV Restriction Factors
16:49

Two Methods of Heterokaryon Formation to Discover HCV Restriction Factors

Published on: July 16, 2012

Hemodialysis of patients with HCV infection: isolation has a definite role

S K Agarwal1

  • 1Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India. skagarwal58@yahoo.co.in

Nephron. Clinical Practice
|November 6, 2010
PubMed

Insights

Hepatitis C virus (HCV) infection is common in hemodialysis patients. This study argues for isolating HCV-infected individuals during dialysis, contrasting with current guidelines.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Public Health

Background:

  • Hepatitis C virus (HCV) prevalence in hemodialysis patients ranges widely (10-60%).
  • Current guidelines, such as those from the CDC, do not recommend isolation for HCV-infected hemodialysis patients.
  • There is ongoing debate regarding the necessity and efficacy of isolating these patients.

Purpose of the Study:

  • To present evidence supporting the isolation of patients with Hepatitis C virus infection during hemodialysis.
  • To address the controversy surrounding isolation protocols for HCV-infected patients in dialysis centers.

Main Methods:

  • Review of existing evidence and guidelines on HCV transmission in hemodialysis settings.
  • Analysis of data supporting the benefits of isolation for infection control.

Main Results:

  • The prevalence of HCV infection in hemodialysis units is significant and variable.
  • Evidence suggests a potential benefit to isolating HCV-infected patients to prevent transmission.

Conclusions:

  • Isolation of HCV-infected patients during hemodialysis may play a crucial role in infection control.
  • Further research and guideline reevaluation are warranted to address the controversy.

More Related Videos

A Protocol for Analyzing Hepatitis C Virus Replication13:04

A Protocol for Analyzing Hepatitis C Virus Replication

Published on: June 26, 2014

Isolation of Primary Rat Hepatocytes with Multiparameter Perfusion Control07:35

Isolation of Primary Rat Hepatocytes with Multiparameter Perfusion Control

Published on: April 5, 2021

Related Concept Videos

Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
Hemodialysis III: Nursing Management01:25

Hemodialysis III: Nursing Management

The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this measurement...
Dialysis01:27

Dialysis

Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Dialysis01:15

Dialysis

Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in critically...